Find the 3 Best Hotels in Hannibal, MO

Garth Woodside Mansion Bed & Breakfast is a historic bed and breakfast offering luxurious accommodations in a meticulously preserved Victorian estate. Located in Hannibal, Missouri, just minutes from Mark Twain-related attractions, we provide guests with an immersive experience combining 19th-century elegance and modern comforts. Our property features eight uniquely decorated guest rooms, gourmet breakfast service, and event hosting capabilities for weddings and special occasions.

Rockcliffe Mansion is a historic Georgian Revival estate offering guided tours and boutique bed and breakfast accommodations. This National Register-listed landmark provides an immersive experience into Gilded Age opulence. Visitors can explore its grand interiors or stay overnight in elegantly preserved chambers.

Main Street Bed & Breakfast offers historic, themed accommodations in downtown Hannibal, Missouri. Our property features three uniquely decorated rooms with modern amenities, complimentary breakfast, and proximity to Mark Twain landmarks. Guests enjoy flexible check-in, personalized service, and walking access to local attractions and dining.